Biofilms in wounds are considered to be one of the major challenges in infection management.

‘Bacteria protected within biofilms are up to 1,000 times more resistant to antibiotics…which severely complicates treatment options.’ (Environ Health Perspect. 2010 Jul; 118(7): A288.)

Currently, either the physical method of debridement is used which is often time consuming,  stressful for the patient and does not remove all of the microorganisms; wound dressings, which are changed on average twice a week ‘…but may take a considerable amount of time to achieve a granulating wound bed,’ (Quality of Life Janice Bianchi –The missing link 2012) or low doses of short term antibiotics that are given with little effect, ‘Therefore there is great potential in this market for an alternative method of biofilm management that ‘suppresses the biofilm without destroying the host cells.’ (J Wound Care vol 17, November 2008). We believe Adtec SteriPlas technology has the potential to not only enable the healing of chronic wounds that are stalled by sub-clinical wound infection (biofilm) but accelerate healing time following intervention with our non-thermal gas plasma .

Earlier in vitro studies carried out by an independent microbiology testing laboratory (Perfectus Biomed) concluded that, ‘Gas Plasma treatment may be an effective method of disrupting Staphylococcus aureus biofilms and has the potential to remove the challenge of persistent infection within a chronic wound thus allowing the wound to heal appropriately.’ (Wounds UK, 2015.). No organisms were detected after a 5 minute treatment with Adtec SteriPlas.

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We are conducting a randomised controlled clinical trial in collaboration with Salford Royal NHS Foundation Trust UK. The primary objective of this project is to evaluate the efficacy of Adtec SteriPlas  on sub-clinical wound infection (biofilm) in patients with diabetic foot ulcers (DFU) compared to those treated with standard care dressings. The secondary objective is to correlate the clinical presentation of long standing DFUs with wound microbiology, biochemistry and histology.

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T: +44 20 8737 5500

F: +44 20 8737 5501


Unit 1, Alice Way,

Hounslow Business Park,

Hounslow, Middlesex

TW3 3UD, United Kingdom

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